CCL2/MCP-1 controls parasite burden, cell infiltration, and mononuclear activation during acuteTrypanosoma cruziinfection

Encephalitis Infiltration During Viral-Induced Neutrophils Promote Mononuclear Cell

Subpleural mononuclear cell infiltration in nonspecific pleuritis.

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Ganglio neuroma With Mononuclear Cell Infiltration – A Diagnostic Dilemma

Ganglio neuromas are childhood Peripheral Neuroblastic tumors (pNTs) derived from precursor cells of the sympathetic nervous system. The differential diagnosis includes Ganglio neuroblastoma. A definite diagnosis & typing is necessary as prognosis depends on it. Here we report a case of Ganglio neuroma in a nine year old child presenting as solitary mediastinal mass. Our study specially shows t...

The phosphorylation of Metaxin 1 controls Bak activation during TNFα induced cell death.

The proapoptotic protein Bak is implicated in the execution phase of apoptosis, a cell death program. Bak is essentially mitochondrial and during early steps of apoptosis undergoes conformational changes that lead to its full membrane integration in mitochondria and the subsequent liberation of pro-apoptotic mitochondrial proteins. Little is known about the partners and mechanisms implicated in...

HSP27 controls GATA-1 protein level during erythroid cell differentiation.

Heat shock protein 27 (HSP27) is a chaperone whose cellular expression increases in response to various stresses and protects the cell either by inhibiting apoptotic cell death or by promoting the ubiquitination and proteasomal degradation of specific proteins. Here, we show that globin transcription factor 1 (GATA-1) is a client protein of HSP27. In 2 models of erythroid differentiation; that ...